Modulation of proteostasis by transcription factor NRF2 and impact in Alzheimer's disease - Paris Redox World Congress 2017 - June 26-27, 2017 - Paris, France

18th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants

Modulation of proteostasis by transcription factor NRF2 and impact in Alzheimer's disease

Ana Isabel Rojo Sanchis Redox

Dr Ana Isabel Rojo Sanchis from the Instituto de Investigaciones Biomédicas "Alberto Sols" in Madrid, Spain will give a strategic presentation about Nrf2 modulation and the impact in Alzheimer's disease during Paris Redox 2017.

Nrf2 has been classically considered as the master regulator of the antioxidant cell response, although it is currently emerging as a key component of the transduction machinery to maintain proteostasis. Nrf2 could be envisioned as a hub that compiles emergency signals derived from misfolded protein accumulation in order to build a coordinated and perdurable transcriptional response. Part of this response is achieved by functions of Nrf2 related to the control of macroautophagy genes.

To know more about Nrf2 and neurological diseases, come & join Paris Redox 2017: www.isanh.net

News

The 19th edition of Paris Redox Congress was a successful event

The 19th edition of Paris Redox Congress was a successful event

The 19th International conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants " Paris Redox 2017" took place at Université Pierre et Marie Curie (UPMC), Paris from on June 26-27...

Special Session on Reactive Sulfide Species (H2S): Marvin Edeas, chairman of the scientific committee will introduce the strategic role of H2S in mitochondria-microbiota intertalk

Special Session on Reactive Sulfide Species (H2S): Marvin Edeas, chairman of the scientific committee will introduce the strategic role of H2S in mitochondria-microbiota intertalk

Marvin Edeas, chairman of the Scientific Committee of Paris Redox 2017 will introduce the first session dedicated to H2S. The intriguing relationship between mitochondria and microbiota and the straetgic role...

Oxidative stress and lens cataract-where are we now?

Oxidative stress and lens cataract-where are we now?

As the world’s population ages, age related nuclear (ARN) cataract has grown to epidemic proportions, placing severe pressures on global and local health systems. Since the initiation of lens cataract...

Modulation of proteostasis by transcription factor NRF2 and impact in Alzheimer's disease

Modulation of proteostasis by transcription factor NRF2 and impact in Alzheimer's disease

Dr Ana Isabel Rojo Sanchis from the Instituto de Investigaciones Biomédicas "Alberto Sols" in Madrid, Spain will give a strategic presentation about Nrf2 modulation and the impact in Alzheimer's disease...

Redox cycling quinones display antibacterial activity against Helicobacter pylori. Is oxidative stress playing a role ?

Redox cycling quinones display antibacterial activity against Helicobacter pylori. Is oxidative stress playing a role ?

This strategic question will be answered during Paris Redox World Congress by Pr Pedro Buc Calderon, Co-Editor in-Chief of the Journal of ISANH and co-chairman of the scientific committee, University of...

Regional fat distribution in women: The relation to metabolic hormones, risk markers and total anti-oxidant status

Regional fat distribution in women: The relation to metabolic hormones, risk markers and total anti-oxidant status

Cardiovascular risk in postmenopausal women has been partly attributed to increased visceral fat accumulation. The team of Dr Saleh conducted a controlled study on healthy women exploring the relation of...

Oxidative stress & spermatogenesis: Presentation of the recent scientific advances

Oxidative stress & spermatogenesis: Presentation of the recent scientific advances

The scientific committee of Paris Redox 2017 is pleased to welcoming Dr Astrid Borchert from Charité-University Medicine Berlin, Germany who will give a presentation about “Male subfertility induced by heterozygous expression of...

Oxidative stress related medical histories of patients with intracranial aneurisms

Oxidative stress related medical histories of patients with intracranial aneurisms

Oxidative Stress (OS) had been suggested to be involved in the occurrence of intracranial aneurisms (ICAs) and their disruption (sub arachnoidal hemorrhage, SAH). As the “classical” clinical profile is a...

Metabolism of reactive sulfide species by "classical" antioxidant mechanisms: a parallel or predominant system?

Metabolism of reactive sulfide species by "classical" antioxidant mechanisms: a parallel or predominant system?

The scientific committee of Paris Redox 2017 is honoured to welcoming Pr Kenneth R. Olson, Emeritus Professor of Physiology at Indiana University School of Medicine - South Bend, USA for the 19th International...

Paradoxical effects of ROS: Increasing tumorigenesis but improving response to some chemotherapies

Paradoxical effects of ROS: Increasing tumorigenesis but improving response to some chemotherapies

In last years, different teams demonstrated that a chronic oxidative stress accelerates aging and increases metastatic spread, by deeply modifying tumour micro-environment. However, while oxidative stress increases tumour development, it...

What is the role of iron overload in initiating oxidative stress in congenital and acquired hemolytic anemias?

What is the role of iron overload in initiating oxidative stress in congenital and acquired hemolytic anemias?

During Paris Redox 2017, Prof. Eliezer Rachmilewitz from the Hematology Department, Edith Wolfson Medical Center at Holon, Israel, will describe the pathophysiology of Iron Overload as the main cause of...

Dissecting the role of the endogenous antioxidant response in lung cancer

Dissecting the role of the endogenous antioxidant response in lung cancer

Dr. Volkan Sayin from NYU school of medicine - Perlmutter Cancer Center, USA will give a strategic presentation about "Dissecting the role of the endogenous antioxidant response in lung cancer" during...

The two faces of oxidative stress: from stress-response to pathogenic damage. The example of glaucoma molecular pathogenesis

The two faces of oxidative stress: from stress-response to pathogenic damage. The example of glaucoma molecular pathogenesis

Prof. Alberto Izzotti from the department of Health Sciences at School of Medicine, University of Genoa, Italy was invited to Paris Redox 2017 to give a talk in the special...

Integrating the Chemical Biology of Reactive Oxygen, Nitrogen and Sulfur Species – Opportunities for Redox Signaling and Precision Medicine

Integrating the Chemical Biology of Reactive Oxygen, Nitrogen and Sulfur Species – Opportunities for Redox Signaling and Precision Medicine

Prof. Martin Feelisch from the University of Southampton, United Kingdom was invited during Paris Redox 2017 to present a talk about "Integrating the chemical biology of Reactive Oxygen, Nitrogen and...

Ocular diseases and truncated thioredoxin rod-derived cone viability factor: A strategic presentation by Pr Thierry Léveillard

Ocular diseases and truncated thioredoxin rod-derived cone viability factor: A strategic presentation by Pr Thierry Léveillard

Dr Thierry Léveillard from the Department of Genetics at Institut de la Vision MR-S 968, Paris will give a presentation about the nucleoredoxin-like 1 gene encodes for two proteins that...

The role of the cystine/glutamate antiporter (CGAP) in controlling redox balance in ocular tissues

The role of the cystine/glutamate antiporter (CGAP) in controlling redox balance in ocular tissues

Oxidative stress and damage plays a major role in the pathogenesis of age-related eye disease such as glaucoma, cataracts and age-related macular degeneration which causes progressive loss of vision. In...

Redox signaling predicts disease progression and patient survival in various conditions

Redox signaling predicts disease progression and patient survival in various conditions

Oxidative stress contributes significantly to various diseases. In cells, free sulfhydryl groups (reduced thiols, R-SH) are the transducers of redox-regulated events; their oxidation status is modulated by interaction with reactive...

Metastatic reprogramming of cancer cells by antioxidants: strategic topic of Paris Redox 2017

Metastatic reprogramming of cancer cells by antioxidants: strategic topic of Paris Redox 2017

Antioxidants, by neutralizing ROS and ROS-induced DNA damages, are thought to protect against cancer. However, clinical studies and a study published by Pr Bergö's team do not support this hypothesis...

Presentation of the new redox tools to investigate the redox state in vascular cells

Presentation of the new redox tools to investigate the redox state in vascular cells

Tools to investigate the complexity of redox and metabolic interactions amongst different tissues in vivo have only recently become available, such as ratiometric redox sensors, metabolic flux analyses, and vertebrate...

Role of the peroxiredoxin 1 in the protection of the telomeres from oxidative stress damage

Role of the peroxiredoxin 1 in the protection of the telomeres from oxidative stress damage

Dr Joachim Lingner from the Ecole Polytechnique Fédérale de Lausanne in Switzerland is one one the invited speaker of Paris Redox World Congress 2017. Dr Lingner is one of the international...

Call for Short Oral, Posters & Innovations Presentations for Paris Redox World Congress 2017

The Scientific Committee of ISANH Paris Redox World Congress 2017 invites all scientists, academics and industrials to present their researches in oxidative stress and antioxidants area during the 19th World Congress...

Marvin Edeas alerted about antioxidant anti-diabetic agents on tumor metastasis

Marvin Edeas alerted about antioxidant anti-diabetic agents on tumor metastasis

Dr Marvin Edeas from Institut Cochin, INSERM U1016, University Paris Descartes, commented the paper published by Dr. Hui Wang, from Department of Endocrinology, Xinqiao Hospital, Third Military Medical University, Chongqing...

Paris Redox 2016 World Congress was a huge success

Paris Redox 2016 World Congress was a huge success

The 17th International conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants " Paris Redox 2016" took place at Institut Pasteur, Paris from June 13 to 15. Pr Marvin Edeas...

Pr Thierry Patrice will talk about the secondary ROS production in patients with cell lung cancers

Pr Thierry Patrice will talk about the secondary ROS production in patients with cell lung cancers

Oxidative stress (OS) had been evaluated in NSCLC using photoproduced singlet oxygen (1O2) deactivating by oxydizing its targets directly or through secondary reactive oxygen species (SOS) production. Either experimentally (orthotopic...

Mitochondria and oxidative stress in age-related muscle loss

Mitochondria and oxidative stress in age-related muscle loss

According Dr Francesca Lo Verso, from the Venetian Institute of Molecular Medicine of Padova in Italy: "Muscle wasting is due to an excessive activation of degradative pathways. It occurs in...

Pr Harald Schmidt will give a talk about Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications

Pr Harald Schmidt will give a talk about Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications

During Paris Redox World Congress 2016, Pr Harald Schmidt from Maastricht University, the Netherlands, will give a presentation about Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications. According to Pr...

Are Reactive Oxygen Species Actually Reactive Sulfide Species?: A strategic question which will be answered by Pr Olson

Are Reactive Oxygen Species Actually Reactive Sulfide Species?: A strategic question which will be answered by Pr Olson

Pr. Kenneth R. Olson is the Emeritus Professor of Physiology, at the Indiana University School of Medicine in South Bend, Indiana, USA. At Paris Redox 2016 he will give a...

Pr Pagano will present his work about the challenges and perspectives of Nox Inhibitors during Paris Redox 2016

Pr Pagano will present his work about the challenges and perspectives of Nox Inhibitors during Paris Redox 2016

During Paris Redox 2016, Pr Pagano from University of Pittsburgh Pennsylvania, USA will present his work on "Nox Inhibitors: from first-in-class Nox2ds-tat to a Peptidic Nox1 & small molecule NOX2i’s –...

Stem cell regenerative decline with aging: role of oxidative stress will be presented by Pr. Muñoz-Cánoves

Stem cell regenerative decline with aging: role of oxidative stress will be presented by Pr. Muñoz-Cánoves

Pr. Pura Muñoz-Cánoves from ICREA and Pompeu Fabra University, Barcelona, Spain is going to give a talk about Stem cell regenerative decline with aging: role of oxidative stress during Paris...

Cutaneous free radical induction by sunlight in different spectral regions and counteraction by systemically or topical applied antioxidants, will be presented by Pr. Meinke

Cutaneous free radical induction by sunlight in different spectral regions and counteraction by systemically or topical applied antioxidants, will be presented by Pr. Meinke

Pr. Martina Meinke from Charité - Universitätsmedizin Berlin, Germany, will give a talk about Cutaneous free radical induction by sunlight in different spectral regions and counteraction by systemically or topical...

Pr. Pedro Buc Calderon will give a presentation about how NQO1 overexpression modulates breast cancer cell sensitivity to quinone-based chemotherapeutic agents

Pr. Pedro Buc Calderon will give a presentation about how NQO1 overexpression modulates breast cancer cell sensitivity to quinone-based chemotherapeutic agents

Pr. Pedro Buc Calderon from the Université catholique de Louvain, Belgium, is going to highlight the topic on how NQO1 overexpression modulates breast cancer cell sensitivity to quinone-based chemotherapeutic agents...

Acute, chronic lung diseases and oxidative stress : targeting respiratory infections, COPD and viral-induced exacerbations of COPD

Acute, chronic lung diseases and oxidative stress : targeting respiratory infections, COPD and viral-induced exacerbations of COPD

Associate Professor Ross Vlahos is a Principal Research Fellow and Head of the Respiratory Research Group in the School of Health & Biomedical Sciences, RMIT University. His research aims to...

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