The 19th edition of Paris Redox Congress was a successful event
The 19th International conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants " Paris Redox 2017" took place at Université Pierre et Marie Curie (UPMC), Paris from on June 26-27. The Scientific Committee chaired by Marvin Edeas, Frédéric Batteux, Pedro Buc Calderon and Miria Ricchetti have welcomed more than 310 academics and industrials representatives coming from 37 countries.
Paris Redox 2017 covered as oral and poster presentations topics of interest and at the end of the congress, several awards were discerned:
Poster Presentation Award:
Dr Francisco Nualart, from the Concepcion Unviersity in Chile was awarded for his poster presentation related to Vitamin C and neuronal oxidative stress alter mitochondrial and cellular size, triggering neuronal death.
According to Dr Nualart presentation: "Vitamin C is the principal antioxidant in the central nervous system and is found in two states: reduced ascorbic acid (AA) and oxidized dehydroascorbic acid (DHA). In the presence of oxidative damage, AA acts as an antioxidant, oxidizing to DHA. Whereas AA is incorporated by neurons through the sodium-dependent vitamin C transporter (SVCT2), DHA diffuses into nerves by glucose transporters (GLUTs).
Our laboratory has shown that accumulation of DHA induces neuronal death in oxidative stress. Here, we analyzed cellular and mitochondrial morphology, because morphological alterations and mitochondrial fission/fusion processes are associated with cell death.The Neuro2a cell line and rat cortical neurons were supplemented with AA and thereafter treated with H2O2. Cell viability was quantified using the XTT method. Cellular distribution of SVCT2 and GLUT1 were analyzed by SIM super-resolution microscopy. Mitochondrial and cellular size was analyzed using the Bounding-Box tool. Oxidation of vitamin C generates neuronal death in 50% of the cells. Oxidation of vitamin C decreased mitochondrial size and volume.
Furthermore, we noted a decrease in mitochondrial activity (MitoTracker, red) with 4D live cell experiments. In conclusion, intracellular DHA generation induces neuronal death. Mitochondrial size, volume, and activity also decrease during vitamin C oxidation."
Dr Nualart's testimonial: "I was pleased to receive word of the award given the poster I presented recently at Paris-Redox 2017, and thank you kindly for this honor. This was my first time participating in a Congress of the ISANH and I found it to be very well organized. The quality of the oral presentations was excellent and the topics dealt with were highly relevant. The scientific research posters also presented relevant ideas and were widely discussed by the attendees. This created an environment with a high scientific level and enhanced the possibility of collaborations with colleagues from different laboratories. Overall, I was pleased to be able to attend this Congress and remain very impressed by its organization and scientific quality.
Short Oral Presentation:
Dr Guillaume Suarez, from the Institute for Work & Health in Switzerland gave a strategic presentation about the fast determination of exhaled air oxidative potential in chronic obstructive pulmonary disease patients
According to Dr Suarez presentation: "The diagnosis and assessment of chronic obstructive pulmonary disease (COPD) is currently based on lung function testing via spirometry which is operator dependent. In a complementary approach we have developed a photonic system that enables the non-invasive determination of the exhaled air oxidative potential (redox balance) that provides access to biochemical information related to oxidative stress occurring in the lung in several respiratory diseases such as COPD and asthma.
These results highlight the potential of the developed system to provide a biochemical-related parameter and help the clinician in the identification and care of respiratory diseases in some occupational settings."
Dr Suarez's testimonial: “For my first participation, Redox 2017 conference has been a wonderful opportunity to exchange scientific ideas in a highly enthusiastic and friendly atmosphere. The variety of topics related to the oxidative stress paradigm were well covered all over the conference by the large number of scientifically relevant contributions. I am glad to participate again next year!”
To access the final program of Paris Redox 2017, please click here.
To access the pictures of 2017, please click here
And all the practical information for 2018 congress will be online soon.
ISANH Team
