Pr Léveillard will present the Induction of cone survival by the truncated thioredoxin Rod-derived Cone Viability Factor through stimulation of aerobic glycosis, during the Antioxidants World Congress 2015

The truncated thioredoxin Rod-derived Cone Viability Factor induces cone survival by stimulating aerobic glycolysis will be the focus of Pr. Léveillard during the 15th International Conference on Oxidative Stress Reduction, Redox Homeostasis & Antioxidants which will be held at Pasteur Institute, Paris on June 22-24, 2015.

"Rod-derived Cone Viability Factor (RdCVF) is an inactive thioredoxin secreted by rod photoreceptors that protects cones. It is a splicing variant of the nucleoredoxin-like 1 gene which also encodes for the thioredoxin RdCVFL that prevents photo-oxidative retinal damage. Because the secondary loss of cones in retinitis pigmentosa is leading to blindness, the administration of RdCVF is a promising therapy independent of the causative gene for this untreatable neurodegenerative disease. Increased glucose promotes cone survival by stimulation of aerobic glycolysis."

To know more about the Antioxidants World Congress 2015, please click here.