Welcome to Antioxidants World Congress 2015

It is a great pleasure to announce the organization of 15th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants, which will be held at Institut Pasteur in Paris, from June 22 to 24, 2015. A workshop dedicated to Oxidative Stress Evaluation will be held on June 22.

We will discuss the role of antioxidants as modulators of redox signaling pathways rather than players that counter "balance" oxidant formation. Indeed, antioxidants affect cells signaling provided by redox processes. Mitochondria consitute a localized signaling domain and produce ROS (i.e. Superoxide and Hydrogen Peroxide), which are signaling molecules generated by the respiratory chain.

During Paris Antioxidants World Congress 2015, we will be interested to understand the ways in which cells respond to oxidative stress and how to prevent damage and cell death, with a particular focus on neurons and neurological conditions, stroke, Alzheimer’s disease, Kidney and Liver pathologies.

ISANH Antioxidants 2015 will highlight the mechanisms of redox regulation of cellular processes. Little is known on the specific targets of ROS and how oxidant and antioxidant signals are transmitted in the cell. To understand mechanisms of redox control and their role in oxidative stress pathologies and aging, it is necessary to identify and dissect the function of the key players of redox processes. We aim that Paris Antioxidants 2015 will contribute to a better understanding of redox control in physiological and pathological states and in ageing, leading to new therapeutic and disease-preventive agents.

Among strategic topics discussed during ISANH Antioxidants 2015:

• Oxidative Stress, Redox Regulation & Modulation and Redox-Active Agents
  
  
• Oxidative Stress & Biomarkers: Imaging of Oxidative Stress in 2015
  • Devices & Methods to visualize the impact of oxidative stress
  • Oxidative stress in vitro vs in vivo: the in vivo trap
  • Oxidative Stress biomarkers in humans
  • Non-invasive methods to evaluate oxidative stress (saliva, urine, hair...)
  • Discussion: can we avoid non-physiological methods to evaluate oxidative stress?
• Oxidative Stress & Stem Cells
  • Impact of Oxidative Stress on the Cell Cycle
  • Effects of Reactive Oxygen Species (ROS) on stem cells dynamics
  • Effect of Oxidative Stress on mitochondria
  • Impact of Antioxidants on stem cells
• Beneficial effects of Oxidative Stress vs deleterious effects of antioxidants
  • Oxidative Stress strategies to fight cancer
  • Strategies to modulate the harmful effects of antioxidants
• New Players in Redox balance
  • DNA damage response proteins & oxidative stress
  • CSB, ATM (DNA Repair)
  • Bc2/CasP9 (apoptosis)
• Oxidative Stress, Ageing & Longevity: Where are we now?
  • Lesson from the Naked Mole Rat Model to study longevity
  • Can longevity be modulated exogenously?
• Oxidative Stress & Chronic Diseases: From Predictive to Preventive Medicine
  
  
• Oxidative Stress, Antioxidants & Innovations
  • News devices, materials and kits to study oxidative stress
  • New synthetic antioxidants for industrial uses - Applications in biofuel, biodiesel and adhesives

Oxidative Stress Imaging in vitro / in vivo
During Paris Antioxidants 2015, we will discuss and present recent advances on visualization and imaging of oxidative stress using new methods. The scientific committee will allocate time for several presentations on the in vivo evaluation of oxidative stress and its impact on proteins, DNA, and mitochondria.

Cell Cycle, Stem Cells & Longevity
The impact of oxidative stress on cell cycle, stem cells regulation, and longevity will be presented. Beneficial and deleterious effects of ROS in key processes related to ageing and longevity will be also discussed.

To conclude this congress, we will organize a round table discussion to answer two strategic questions:

• Oxidative Stress and Antioxidants: The “positive” and “negative” sides of the coin for antioxidants
• The subtle balance between redox homeostasis, ROS, and mitochondria homeostasis

With this exciting program, we wish to meet you in Paris next June.

Marvin Edeas - Chairman of the Scientific Committee

Miria Ricchetti – Chairperson of the Local Organizing Committee