Redox Medicine 2024: Insights from Poster Presentations

POSTERS TEMPLATE 2024

The field of redox medicine focuses on the role of oxidative stress and redox signaling in health and disease. Recent research has provided new insights into the mechanisms and potential therapeutic applications of redox-active compounds. The collection of poater presentations provides a comprehensive overview of the latest advancements in Redox Medicine.

1. Metallofulleronols as a New Generation of Radiotherapeutics: Protecting Effect on Radiolytically Induced Hemolysis of Human Erythrocytes

Michał Żebrowski, University of Warsaw, Poland

This research explores the protective effects of metallofulleronols against radiolytically induced hemolysis in human erythrocytes, proposing a new class of radiotherapeutics. It offers a novel approach to radioprotection, potentially improving the safety and effectiveness of radiotherapy in cancer treatment.

2. A Synthetic Thiol Molecule Releasing N-Acetyl-L-Cysteine (NAC) and Cysteamine (MEA) with Antiviral and Anti-Inflammatory Activity

Sofia Masini, University of Urbino Carlo Bo, Italy

This study investigates a synthetic thiol molecule that releases NAC and MEA, demonstrating antiviral and anti-inflammatory properties. It introduces a multifunctional therapeutic agent with potential applications in treating viral infections and inflammatory diseases.

3. Antiproliferative Effect of Phenolic Compounds from Garlic on Human Breast Cancer Cells through the Modulation of Oxidative Stress

Yasmany Armas Diaz, Autonomous University of Guerrero, Mexico

This research examines the antiproliferative effects of garlic-derived phenolic compounds on breast cancer cells, focusing on their ability to modulate oxidative stress. It provides insights into the use of natural compounds for cancer therapy, emphasizing the role of oxidative stress modulation.

4. Nuclear Localization of Glyoxalase 2 and its Possible Role as Survival Factor in Human MCF7 Breast Cancer Cells

Brenda Romaldi, Polytechnic University of Marche, Italy

This study investigates the nuclear localization of glyoxalase 2 and its role as a survival factor in breast cancer cells. It enhances understanding of the molecular mechanisms underlying cancer cell survival, offering potential targets for therapeutic intervention.

5. Resveratrol Regulates the Level of Expression of Genes Related to Appetite Regulation in Hypothalamus of Obese Mice

Monica Espinoza-Rojo, Autonomous University of Guerrero, Mexico

This research explores how resveratrol affects gene expression related to appetite regulation in the hypothalamus of obese mice. It suggests a potential role for resveratrol in managing obesity through genetic regulation of appetite.

6. Curcumin Improves Redox Status in the Periphery and Regulates the Expression of Appetite-Regulated Molecules in the Hypothalamus of Diabetic Mice

Yaccil Adilene Flores-Cortez, Autonomous University of Guerrero, Mexico

This study examines the effects of curcumin on redox status and appetite-regulating molecules in diabetic mice. It highlights the therapeutic potential of curcumin in diabetes management through modulation of redox status and appetite regulation.

7. HM-Chromanone Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Modulating Hepatic Lipogenesis and Oxidative Stress in High Fat Diet-Fed Mice

Ji Sook Han, Pusan National University, Republic of Korea

This research investigates the effects of HM-Chromanone on hepatic lipogenesis and oxidative stress in a mouse model of steatotic liver disease. It proposes a new therapeutic candidate for metabolic liver diseases, focusing on oxidative stress modulation.

8. New Insight into Bilirubin as a pH-Dependent Antioxidant in Micellar and Liposomal Systems

Wojciech Witkowski, University of Warsaw, Poland

This study explores the antioxidant properties of bilirubin in different pH environments using micellar and liposomal systems. It provides new understanding of bilirubin's role as an antioxidant, which could inform its therapeutic use.

9. Improving the Nature - Modifications of Natural Polyphenols Leading to Increase of Lipophilicity

Pawel Przybylski, University of Warsaw, Poland

This research focuses on modifying natural polyphenols to increase their lipophilicity, enhancing their therapeutic potential. It enhances the bioavailability and effectiveness of polyphenol-based therapies.

10. Oxygen Consumption and Oxidative Stress in Osteoprogenitor Cells Exposed to an Osteoinductive Biomaterial

Renata Neves Granito, Federal University of São Paulo, Brazil

11. Setting-Up of 3D Organoid Culture Model in Cancer Compared to 2D System

Giulia Casari, Polytechnic University of Marche, Italy

This study compares 3D organoid culture models to traditional 2D systems in cancer research. It provides a more accurate model for studying cancer biology and drug responses.

12. Antidiabetic Activity of Passiflora edulis Seed Oil in Zebrafish

Elaine Luiza Santos Soares Mendonça, Federal University of Alagoas, Brazil

This study evaluates the antidiabetic properties of *Passiflora edulis seed oil using a zebrafish model. It suggests potential new natural treatment options for diabetes.

13. NOX2 and NOX4 Expression in Monocytes and Macrophages: Extracellular Vesicles in Signaling and Therapeutics

Ankush Prasad, Palacký University, Czech Republic

14. Nitroreductase-Activated Fluorescent Probes for Imaging Hypoxia in Cancer Cells

Małgorzata Brindell, Jagiellonian University, Poland

15. Metabolic Effects of Elevated Sulfide are not Mediated through Skeletal Muscle AMPK or Insulin Signaling in High Fat Fed TST−/− Mice

Hongling Liu, University of Edinburgh, United Kingdom

This research examines the metabolic effects of elevated sulfide in high fat-fed mice, focusing on skeletal muscle AMPK and insulin signaling. It provides insights into the metabolic pathways affected by sulfide, contributing to the understanding of its role in metabolic diseases.

16. Nitric Oxide – Dependent S-Nitrosation Mediated by Microperoxidase-11

Maria Oszajca, Jagiellonian University, Poland

17. Non-Ionizing Radiation Exposure Induces Resistance to Oxidative Stressor Menadione

James Harry Skoyles, Aston University, United Kingdom

18. Influence of Environmental Stressor on Endothelial Senescent Cells

Olga Mazuryk, Jagiellonian University, Poland

19. Mitochondrial Transplantation as Potential Therapeutic Solution to Ischemia-Reperfusion Injury in Kidney and Brain

Anne Borgne-Sanchez, Mitologics, France

20. Hydroxycinnamic Acid Derivatives as Bifunctional Antioxidants and Iron Chelators for UVA Photoprotection In Skin Cells

Charareh Pourzand, University of Bath, United Kingdom

21. Myeloperoxidase Inhibition as a Therapeutic Target for Alzheimer's Disease: Exploration if an in vitro Model Using HMC3 Cells

Astrid Mayleth Rivera Antonio, Instituto Politécnico Nacional, Mexico